EFFECT OF MANIHOT ESCULENTA LEAF EXTRACT ON EXPRESSION OF GLUTATHIONE GENE IN STEPTOZOTOCIN-TREATED RAT
Abstract
ABSTRACT
Diabetes mellitus (DM) is a major global health challenge characterized by chronic hyperglycemia due to defects in insulin secretion, action, or both. The study aimed to investigate the effect of Manihot esculenta leaf extract on the expression of glutathione-related genes in streptozotocin-induced diabetic rats. A total of 30 rats were randomized into six equal groups. Diabetes was induced in rats using streptozotocin (STZ). After the induction of all the animals, they were treated within 28 days according to the experimental design. The study revealed significant differences (p
Full-Text Access Notice
In accordance with the NERD Policy on promoting peer-reviewed publication, public access to the full text of a project, thesis or dissertation is restricted for three years, allowing the author and supervisors sufficient time to pursue peer-reviewed publication.
During this period, researchers with legitimate academic or research purposes may request authorisation directly from the author to enable NERD to release the indexed full texts of the work using the form below.