ASSOCIATION OF ABO BLOOD GROUP AND HAEMOGLOBIN GENOTYPE WITH MALARIA INFECTION AMONG UNDERGRADUATES AT AAUA, AKUNGBA-AKOKO
Abstract
This study determined the socio-demographic characteristics and the association between blood group, haemoglobin genotype, haemoglobin antigen, packed cell volume (PCV), and malaria parasite infection among 250 respondents. The majority of participants were female (68.8%) and within the 18–23 age group (79.6%). Blood group O⁺ (67.6%) and genotype AA (88.4%) were most prevalent. Malaria parasite prevalence was 38.0%. Statistical analysis showed no significant association between blood group and malaria infection (p = 0.48), nor between haemoglobin genotype (p = 0.29) or haemoglobin antigens (p = 0.38) and malaria infection. However, PCV levels were significantly lower in malaria-infected individuals (mean = 34.64%) compared to uninfected individuals (mean = 39.95%), with a statistically significant difference (p = 0.01), suggesting a link between malaria and anaemia. while malaria infection did not show significant associations with blood group or genetic factors in this cohort, its impact on PCV highlights its clinical relevance in haematological health monitoring.
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