BACTERIURIA PROFILE OF PATIENTS DIAGNOSED WITH BENIGN PROSTATIC HYPERPLASIA IN UMUAHIA.

ABSTRACT Benign prostrate hyperplasia is one of the most common benign diseases of the prostate gland (and probably of the entire genitourinary tract) and over time affects a considerable majority of men. This study determined the bacteriuria profile of patients diagnosed with benign prostatic hyperplasia. A total of 50 subjects were recruited into the study by systemic random sampling method. Urine samples were collected from a total of 50 benign prostatic hyperplasia patients into sterile universal containers and the samples were processed immediately after collection, and data generated was analyzed statistically. Investigation shows that fourty three out of the fifty samples had microbial growth, giving a bacteriuria prevalence of 86%. The isolates were identified using standard bacteriological methods as Pseudomonas aeruginosa, Escherichia Coli, Enterococcus faecalis, Klebsiella aerogenes, Staphylococcus aureus, and Lactobacilli. Of all the bacteria isolates, Staphylococcus aureus was found to be the most commonly isolated (34.8%), followed by Pseudomonas aeruginosa and Klebsiella aerogenes (18.6% respectively). Escherichia coli, Enterococcus faecalis, and Lactobacilli were the least isolated organisms (9.3% respectively). The results of the antibiotic susceptibility pattern showed that all microbial isolates excluding Pseudomonas aeruginosa, were highly sensitive to Gentamycin. High resistance was seen in Ampicillin, Augmentin, Ceporex, Tarivid, Nalidixic acid, and Reflacin. These findings highlight the need for tailored antibiotic therapy and efforts to prevent antibiotic resistance among individuals with BPH.