THE EFFECT OF COLD WATER ON THE LIPID PROFILE OF AN ALBINO WISTAR RAT

This study investigate the effect of cold water consumption on the lipid profile of male and female albino wistar rats, focusing on changes in cholesterol, triglycerides, low-density lipoproteins (LDL), high-density lipoproteins (HDL), and very low-density lipoproteins (VLDL). Four groups of rats, Male : Group I (control group 30 days), Group II ( Experimental group 30 days), Group III ( control group 60 days) and Group Iv ( Experimental group 60 days) and FEMALE: Group I (control group 30 days), Group II ( Experimental group 30 days), Group III ( control group 60 days) and Group Iv ( Experimental group 60 days). Were acclimatized for 14 days, and administered blue rose table water (3 mL per rat, twice daily. Room temperature water for the control group and cold water for the test group) for the same durations. Blood samples were collected post-anesthesia after a 12-hour fasting period for biochemical analysis.Results revealed that cold water intake did not significantly affect total cholesterol levels but led to nuanced, gender-specific effects on other lipid components. Males exhibited a short-term increase in triglycerides, attributed to acute metabolic stress and fat mobilization, while females demonstrated prolonged effects on triglycerides, LDL, and HDL levels, suggesting different regulatory mechanisms potentially influenced by hormonal factors. Notably, VLDL showed no significant change in males but a prolonged effect in females, indicating the presence of sex-specific biochemical pathways. These findings underscore the differential regulation of lipid metabolism under cold water exposure, emphasizing the need for further exploration of gender differences in metabolic responses to cold-induced stress.