EFFECT OF AQUEOUS EXTRACT OF DIALIUM GUINEENSE (AFRICAN VELVET TAMARIND) ON LEAD INDUCED NEPHROTOXICITY IN ADULT WISTAR RAT
Abstract
This study aimed to access the potential nephroprotective effects of african velvet tamarind fruit extract on the kidney and adrenal gland in Wistar rats subjected to lead-induced nephrotoxicity. A total of thirty (24) wistar rats obtained from animal House of Department of Anatomy, Faculty of Basic Medical Sciences, used for this study. The rats were divided into six (6) groups. Results showed a significant decrease in the body weight of rats in treated groups. Histological findings of kidney and adrenal gland showed normal architecture of kidney in control group A and C indicating the non toxic effect of african velvet tamarind fruit on the kidney and adrenal gland. Group B (lead only) showed a severe degenerative changes like severe necrosis, severe focal area of hemorrhages and severe atrophy stating danger of lead exposure to the kidne
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