ASSESSMENT OF PLATELET COUNT AND FIBRINOGEN LEVEL AMONG PREGNANT WOMEN ATTENDING ANTENATAL CLINIC AT ABIA STATE UNIVERSITY TEACHING HOSPITAL ABA, NIGERIA

Student: Chinwendu Rebecca John-Offor
Supervisor: Dr Okezie Okamgba
HOD: Dr Okezie Okamgba
Department of Medical Laboratory Science
Health Sciences
Abia State University, Uturu, Abia State

Abstract

ABSTRACT Pregnancy is a normal physiological process known to alter haemostatic mechanism. This study investigated the platelet count and fibrinogen level among pregnant women with a predisposition towards bleeding diathesis. A total of 100 subject were recruited for the study and there were 50 pregnant women who were classified as test subjects and 50 nonpregnant women who served as control. Platelet count and fibrinogen level were assessed using automated machine and Clauss method respectively and data generated were statistically analyzed using student t-test and ANOVA. platelet count 223.63±7.55×10^9/L in the first trimester was significantly reduced in comparison with 217.00±3.21×10^9/L in the second trimester and statistically significantly reduced in comparison with 208.15±6.17×10^9/L for third trimester (p

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