INVIVO ANTI PLASMODIAL ACTIVITY OF LEAF EXTRACT OF AQUEOUS PAPAYA
Abstract
This study evaluates the in vivo antiplasmodial activity of aqueous leaf extract of Carica papaya. Malaria, caused by Plasmodium parasites, remains a major public health challenge, particularly in sub-Saharan Africa. The increasing resistance to conventional antimalarial drugs has necessitated the search for alternative therapies, including medicinal plants. The study involved the extraction of papaya leaves using aqueous methods and administration to infected experimental animals. Parasite levels were monitored and compared with standard antimalarial drugs. Results showed a significant reduction in parasitemia in treated groups, indicating that the extract possesses antiplasmodial properties. The study concludes that aqueous leaf extract of papaya may serve as a potential source of antimalarial agents.
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