EFFECT OF TANNINS ISOLATED FROM SENNA OCCIDENTALIS ON UREA AND ELECTROLYTES CONCENTRATION OF NORMAL ADULT WISTER RATS
Abstract
ABSTRACT
This study investigated the effects of tannins isolated from Senna occidentalis on urea and electrolyte
concentrations in normal adult Wistar rats. The rats were divided into three groups: control, low-dose
tannins (Y mg/kg), and high-dose tannins (Z mg/kg). After two weeks of treatment, serum urea,
creatinine, sodium, bicarbonate, hydrogen, and calcium levels were measured. The results showed that
tannins significantly reduced serum urea and creatinine levels, indicating potential nephroprotective
effects. Additionally, tannins improved electrolyte balance by increasing sodium, bicarbonate, and
calcium levels. These findings suggest that Senna occidentalis tannins may have beneficial effects on
kidney function and electrolyte homeostasis in normal adult Wistar rats. Further studies are needed to
elucidate the mechanisms underlying these effects and explore potential therapeutic applications.
for liver-related conditions.
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