RENAL PROTECTIVE EFFECT OF MEXICAN SUNFLOWER LEAF(TITHONIA DIVERSIFOLIA) EXTRACTON MALE ALBINO RAT
Abstract
Tithonia diversifolia, an annual plants of medicinal herbs from Astericeae family known as Mexican sunflower which have its toxic and medicinal properties, exhibit potent antimicrobic, antiparasitic, antidiarrhea, anti inflammatory activities and it is also used in the treatment of pulmonarydiseases.Thisstudy wasdesigned to investigate the renalprotective effect of Tithonia diversifolia leaf extract on albino rat kidney. Twenty animals were randomly assigned into five groups,witheachgroupconsistingof4animalseach.GroupAservedasthecontrolgroupwhich was incorporated with normal saline with the aid of cannula, Group B had methanol extract of Tithoniadiversifolia,GroupChadmethanolextractofTithoniadiversifolialeaf,GroupDhadn-hexane extract of Tithonia diversifolia leaf while Group E had n-hexane extract of Tithonia diversifolia leaf, all at different body weight. The animals were fed for seven days, at the end of experimental period, the animals were sacrificed by cardiac puncture, and blood collected for biochemical estimation. Creatinine and urea concentration were determined in blood serum and probabilityvaluestakenat(p
Full-Text Access Notice
In accordance with the NERD Policy on promoting peer-reviewed publication, public access to the full text of a project, thesis or dissertation is restricted for three years, allowing the author and supervisors sufficient time to pursue peer-reviewed publication.
During this period, researchers with legitimate academic or research purposes may request authorisation directly from the author to enable NERD to release the indexed full texts of the work using the form below.