EFFECT OF BLACK SEED (NIGELLA SATIVA) EXTRACT ON THE LIPID PROFILE OF ALBINO WISTAR RAT.
Abstract
This study aimed to determine the effect of Nigella sativa aqueous extract on lipid
profile which was evaluated by total cholesterol and triglycerides. In this study,
eight (8) male albino rats were randomly divided into 4 groups (2 each). The
control group were fed orally with black seed aqueous extract a n d 0.1mg/kg,
0.2mg/kg and 0.25mg/kg for group 2, 3 and 4 respectively. At the end of fourteen
days the rats were sacrificed and their blood samples were collected through
cardiac puncture. Statistical analysis were done through one-way anova using
SPSS. The results reveled that there was no significant difference (p0.05) in total
cholesterol and triglycerides in treated groups when compared to the control
group. There was a significant reduction (p0.05) in the levels of total cholesterol
and triglycerides in group four animals when compared to the control. This results
suggests that blabhck seed Nigella sativa has a favorable effect on lipid profile
and seemed potential target for the treatment of hyperlipidemic condition.
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