RETICULOCYTE COUNT OF SICKLE CELL PATIENT ATTENDING HEMATOLOGY DAY CARE UNIT, UNIVERSITY COLLEGE HOSPITAL, IBADAN, OYO STATE.
Abstract
Sickle Cell Disease (SCD) is a hereditary blood disorder characterized by the presence of an
abnormal form of hemoglobin, known as hemoglobin S (HbS). It is one of the most common
genetic disorders worldwide, particularly prevalent among individuals of African,
Mediterranean, Middle Eastern, and Indian descent. The aim of this study is to evaluate and
analyze reticulocyte count in sickle cell patients, its objectives are; to assess the reticulocyte
count in a cohort of sickle cell patients and compare them with a control group of individuals
without sickle cell, to investigate reticulocyte count and clinical manifestations of sickle cell
disease, and to examine the use of drugs and specific drugs used by sickle cell patients. The
research adopts a cross-sectional study design to evaluate the reticulocyte count of sickle cell
patients. The result of analysis revealed that the reticulocyte count and percentage of sickle cell
patients is between 81-90 and 6.1-6.9 respectively. The reticulocyte count and percentage of
the control group is 3.0-9.0 and 0.3-0.9 respectively. The result of analysis revealed that 50.0%
of the participants are diagnosed with HbS and are on drugs, and 30.0% take folic acid, while
20.0% take astymin and vitamin C respectively. It is concluded that participants with sickle
cell disease have a reticulocyte count of 81-90, and participants in the control group have a
reticulocyte count of 3.0-9.0. It is recommended that patients should be educated about the
significance of reticulocyte count, and the importance of monitoring and adhering to treatment
plans
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