EFFECTIVENESS OF DIFFERENT TYPES OF CHEMOTHERAPHY REGIMENS ON MALIGNANT TUMOR IN BREAST CANCER PATIENTS
Abstract
ABSTRACT
Breast cancer is a complex disease that affect millions of individuals worldwide. Nigeria has one
of the highest mortality rates of breast cancer and the highest in Africa. The effectiveness of dif-
ferent types of chemotherapy regimens that reduce malignant tumor size in breast cancer patients
remains a subject of investigation worldwide while chemotherapy is one of the most commonly
used treatment approach for breast cancer patients with the aim to shrink malignant tumor. This
research aims to investigate which chemotherapy regimen is effective in reducing malignant tu-
mor in breast cancer patients after chemotherapy using ANOVA. We conduct a research on 9
breast cancer patients at Aminu Kano Teaching Hospital, Kano(AKTH) with 3 chemotherapy
regimens which are: Cyclophosphamide + Doxorubicin, Epirobicin + Cyclophosphamide and
Paclitaxel, Each regimen is assigned to 3 patients and we used One-Way ANOVA to analyze
the mean patients tumor size before and after chemotherapy and see which regimen is effective
in shrinking malignant tumor after chemotherapy. Based on the analysis that we made in this
research we find out that all the three (3) chemotherapy regimens are effective in reducing ma-
lignant tumor size in breast cancer patients.
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