PHYTOCHEMICAL SCREENING AND ANTI BACTERIAL EFFICACY OF GUAVA LEAVES EXTRACT ON SOME ENTERIC BACTERIA (E.COLI AND SHIGELLA DYSENTRIAE)
Abstract
The aim of this study was to examine the phytochemical and antimicrobial properties of extracts of Psidium guajava leaves against some clinical bacterial isolates. The plant leaves were extracted in two solvents namely; aquouse and ethanol. The pathogenic bacterial isolates were Escherichia coli, and Shigella dysenteriae all isolated from Clinical Isolates. The phytochemicals analysis should the presence tannins, flavonoids, alkaloids, saponins, glycosides, Steroids, Anthraquinones and in different proportions. The mean antibacterial activity of the extracts in vitro showed that the ethanolic extract was most efficacious at 200 mg concentration, inhibiting ), E. coli (20.0 mm), and Shigella (18.3). The aqueous extract at 100 mg concentration inhibited E. coli (9.0 mm) and Shigella (10.0).This study has revealed that the leaves extract of P. guajava contains antibacterial and phytochemical substances which can be harnessed in satiation of human quest for better and healthier living.
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