PROTECTIVE EFFECT OF SOY BEAN (GLYCLINE MAX) ON ALCOHOL INDUCED TOXICITY OF THE BRAIN TISSUE: HIPOCAMPUS AND NEUROBEHAVIORAL STUDIES OF ADULT FEMALE ALBINO RAT
Abstract
ABSTRACT
Alcoholic liver damage has become common among the populace. the economic situation and poverty level have made alcohol consumption high among the population; as people tend to resort to high alcohol consumption to give them succor. soybean is known for its pharmacologic and nutritional properties. the aims of this study were to analyze the phytochemicals present in soybean and investigate the effect of soybean against alcohol-induced liver disease. in this study, twenty-four (24) male albino wister rats weighing (200-220 gm) were divided into four (4) groups: group 1 served as normal control and received only distilled water, group 2 as positive control and was given ethanol plus vitamin c (200 mg/kg, oral),group 3, the test group was given ethanol plus soymilk (2000 mg/kg, oral), and group 4, the negative control was given ethanol alone (2000 mg/kg, oral) for twenty one (21) days. albumin, total bilirubin, conjugated bilirubin, aspartate transaminase (ast), alanine transaminase (alt), and alkaline phosphatase (alp) levels were evaluated using rx monza analyzer and standard laboratory kits from randox laboratories, uk. the results showed a significant decrease in levels of serum bilirubin, and a significant decrease (p
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