ANTI-INFLAMMATORY EFFECT OF AQUEOUS-METHANOLIC EXTRACT OF ANNONA MURICATA (SOURSOP) LEAVES ON KIDNEY FUNCTION PARAMETERS IN FORMALIN-INDUCED INFLAMMATION AND OEDEMA IN MALE RATS
Abstract
This study investigates the anti-Inflammatory effect of aqueous-methanolic extract of Annona muricata (Soursop) leaves on kidney function parameters in formalin-induced inflammation and oedema in male rats, a model commonly used to mimic inflammatory kidney dysfunction. Analysis of creatinine, urea, electrolytes (potassium, sodium, and chloride), and bicarbonate concentrations were carried out using methods in the recommended kits. Data were presented as a mean ± standard error of mean of five determinations. Statistical analysis was carried out using one way analysis of variance (ANOVA). Difference were statistically significant at p
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