EFFECT OF VIRGIN COCONUT OIL AND LEAD ACETATE ON THE KIDNEY OF ADULT FEMALE WISTAR RAT

Student: Mayowa Roshidat Ibrahim
Supervisor: Prof Wasiu Akintunde
HOD: Dr Adejoke Onaolapo
Department of Department of Anatomy
Faculty of Basic Medical Sciences
Ladoke Akintola University of Technology, Ogbomoso, Oyo State

Abstract

Leachate is a liquid, generated during the process of lead-acid battery recycling. It contains mixture of metals. The liquid is leached from heap of auto-battery recycling wastes into nearby water bodies. Also, the components of the leachate may percolate through the soil, polluting these water bodies and get access to food chains. Leachate from a municipal battery recycling site may be implicated as a source of mixed-metals which, when indiscriminately dumped or improperly recycled, might have access to water bodies and food chains. They may consequently get into humans by drinking water or by ingestion and/or inhalation and thus induce toxic effects on the human organ. This experimental study investigated effects of Battery leachete on liver of adult female Wistar rats. Twenty five adult male Wistar rats were divided into five groups A, B, C, D and E (n=5), each group weighing 180–200g. The Wistar rats were subjected to different dosage of battery leachete in order to ascertain the possible morphological changes in the liver following the radiation. The rats in group A were regarded as the control group and they received only distilled water throughout the period. The rats in Group B, C, D and E were the experimental groups that received the dosage (1ml of VCO and 1ml of Lead acetate) for 5 weeks respectively. The rats were then sacrificed by cervical dislocation and the kidneys were excised and weighed before fixing in 10% formal saline and were processed for microscopic study. This study reveals that the exposure to electromagnetic wave has the potential to cause damage to biological tissues by altering their structure and function. However, this impact is not reflected in the general body weight, as statistical analysis reveals that the P-Value remains insignificant across all groups during the initial weeks of exposure when compared to the control group. This suggests that while EMVs may induce cellular and structural changes at the microscopic level, these effects do not immediately translate into measurable changes in overall body weight during the early stages of exposure. The data indicates that the weights of the left and right kidneys were not significantly affected by exposure to electromagnetic waves. However, notable differences in kidney weight were observed across all experimental groups when compared to the control group, except for Group E's left kidney. This implies that electromagnetic wave exposure had a slight to no measurable impact on kidney weight throughout the study. The histomorphological examination of the kidneys across all experimental groups reveals that exposure to electromagnetic waves does not result in significant structural damage. ​ This study conclude that the impact of electromagnetic waves on kidney health is a complex and evolving area of research. While studies have provided some insights into possible physiological effects, including alterations in kidney histomorphology, definitive evidence regarding the long-term consequences, particularly for cardiovascular health, remains limited. As technological advancements continue, more research is being conducted on how electromagnetic wave exposure affects the body, underscoring the need for further investigation into its specific effects on kidney function.

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