ANTIBACTERIAL ACTIVITY OF GONGRONEMA LATIFOLIUM (UTAZI) LEAVES EXTRACT AGAINST ESCHERICHIA COLI.
Abstract
ABSTRACT
Gongronema latifolium (Utazi) leaf extract is a highly medicinal plant that claims effective therapy for the treatment of various diseases by traditional herbalists worldwide. This study aims to screen Gongronema latifolium (Utazi) leaf extract for antibacterial activity against Escherichia coli. The dried leaf powder of Gongronema latifolium was extracted using ethanol and water at room temperature, The antibacterial effects of the extracts were determined using the agar well diffusion method at different concentrations. The results from the phytochemical test showed the presence of alkaloids, flavonoids, saponins, tannins, and terpenoids in both ethanol and aqueous extract but steroids were only present in ethanol extract. From the data, the antibacterial effect of the control chloramphenicol (25.0±0.5) was significantly different (p
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