EVALUATION OF SERUM MAGNESIUM LEVELS AMONG PREGNANT AND NON-PREGNANT WOMEN ATTENDING ANTENATAL CARE AT FAITH ALIVE FOUNDATION HOSPITAL, JOS
Abstract
Magnesium is crucial for human biochemical and physiological processes, including energy metabolism, fatty acid synthesis, neuromuscular excitability and nerve impulse transmission. It is the fourth most abundant cation and the second most prevalent intracellular cation found in human tissues. Magnesium plays a crucial role in maternal and foetal health, with complex interactions between metabolism and clinical symptoms. Deficiency of this ion can cause adverse outcomes during pregnancy including preterm birth, leg cramps, constipation, pre-eclampsia, fatigue, weakness, hypertension, appetite loss, insomnia, nausea, vomiting and diarrhoea. The study aimed to evaluate serum magnesium levels among pregnant and non-pregnant women attending antenatal clinic at Faith Alive Foundation Hospital Jos, Nigeria. The cross-sectional comparative study involved 100 participants, including 50 cases and 50 controls. Ethical approval was obtained from the Ethical Committee of Faith Alive Foundation Hospital Jos. Data was collected from participants using a well-designed questionnaire. Whole blood was collected from the antecubital fossa using a sterile syringe and needle. Automated Chemistry analyzer (iMagic-M7) was used for the estimation of serum magnesium levels using the Agape Magnesium reagent kit. It was observed that pregnant women had significantly lower (P
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