GENOTOXICITY EFFECT OF ROUNDUP HERBICIDES ON PANICUM MILIACEUM L. (MILLET)
Abstract
ABSTRACT
This study revealed the genotoxic effects of Roundup herbicide on miller (Panicum miliaceum) by analyzing Deoxyribonucleic acid (DNA) damage across varying herbicide concentrations (0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, and 1.0). Using Deoxyribonucleic acid gel electrophoresis and dendrogram clustering analysis, the study provides insights into the dose-dependent response of millet Deoxyribonucleic acid to herbicide exposure. Gel electrophoresis revealed distinct banding patterns, with thick, intense bands between 1-500 base pairs in the 0.4, 0.7, and 0.9 treatments, indicating substantial Deoxyribonucleic acid fragmentation. Dendrogram analysis further supported these findings, showing distinct clustering patterns for samples exposed to concentrations (0.4, 0.7 and 0.9) without similar clustering with the control treatment. These results suggest that Roundup induces genotoxic effects in millet in a concentration-dependent manner, with higher concentrations potentially triggering Deoxyribonucleic acid repair or adaptive responses. This study recommended the need for careful regulation of herbicide application rates to minimize genetic risks in crop plants, providing valuable insights for sustainable agricultural practices and food security.
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