ASSESSMENT OF CLOTTING PROFILE IN WOMEN WITH INFERTILITY IN UNIVERSITY OF MEDICAL SCIENCES TEACHING HOSPITAL ONDO CITY, ONDO STATE.
Abstract
ABSTRACT
Infertility affects approximately 8-12% of couples worldwide, with various factors contributing
to this condition. Recent studies suggest a potential link between coagulation abnormalities and
fertility issues. This study aimed to investigate the relationship between clotting profiles and
infertility in women in Ondo University of Medical Science, Ondo State Nigeria.
A case-control study was conducted involving 50 women diagnosed with infertility (test group)
and 50 fertile women (control group). Prothrombin Time (PT) and Activated Partial
Thromboplastin Time (APTT) were determined using the Lee and White method (AGAPE) kits
for all participants. The study also examined associations between clotting profiles and type of
infertility (primary vs secondary) as well as age. Significant differences were observed in both
PT and APTT between infertile and fertile women. The mean PT for infertile women was 15.72
± 3.36 seconds compared to 13.10 ± 1.64 seconds in fertile women (p
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