ASSESSMENT OF SOME HAEMATOLOGICAL PARAMETER IN MALARIA PATIENTS IN ABA AREA

ABSTRACT Malaria, which is responsible for substantial amount of deaths in endemic countries, has been shown to have both direct and indirect effects on the haematological parameters. Notwithstanding, some haematological parameters among populations living in malaria endemic regions have not been described consistently, as a standard for measuring malaria burden. Based on the above fact, this study was designed to assess some hematological changes and their diagnostic values in malaria infected patients. A total of 100 patients were recruited for the study. Fifty patients had P. falciparum malaria while fifty were negative and were used as controls. Ethical approval and informed consent of the subjects were obtained. Parameters assessed were HB, PCV, RBC, RDW, WBC, Neutrophils, Lymphocytes, Monocytes, Eosinophils and Platelet. Blood collected from each subject was tested for malaria parasite using the preparation of thick blood film and estimation of Full Blood Count by automated analyzer (Minray BC-500 analyzer). Values obtained were statistically analyzed using Statistical package of Social Sciences (SPSS Version 21.0). From this study, results showed that the mean value of PCV (36.79 ± 4.78%), Hb (10.75 ± 1.63 g/dl), RBC (4.98 ± 0.69 × 10¹²/L) WBC (4.91 ± 1.71 × 10⁹/L) and Neutrophils (39.12 ± 6.20) in malaria infected subjects were statistically reduced when compared to control respectively (p>0.05). PCV (45.08 ± 2.81%), Hb (45.08 ± 2.81 g/dl), RBC (5.67 ± 0.63 × 10¹²/L), WBC (7.26 ± 2.34 × 10⁹/L) and Neutrophils (56.43 ± 8.27). The mean value of lymphocytes (52.84 ± 5.54), monocytes (5.48 ± 2.12), and eosinophils (3.01 ± 2.19) in malaria infected subjects were statistically increased when compared to control respectively (p